Publications

101 F Anjum, A Carroll, S. Young, LE Flynn and BG Amsden, “Tough semi-synthetic hydrogels for stem cell delivery for chondral defect repair” Macromolecular Bioscience, accepted.
100 JP Chesterman and BG Amsden, “Triethylamine-based catalysts for the melt polymerization of carbonate monomers” Polymer Chemistry, accepted.
99 BG Amsden and D Marecak, “Long-term sustained release from a biodegradable photo-cross-linked network for intra-ocular corticosteroid delivery” Molecular Pharmaceutics, 13(9) (2016) 3004-3012.
98 JWS Hayami, SD Waldman, and BG Amsden, “Chondrocyte generation of cartilage-like tissue following photoencapsulation in methacrylated polysaccharide solution blends” Macromolecular Bioscience, 16(7) (2016) 1083-1095
97 F Chen, G Hochleitner, T Woodfield, J Groll, P. Dalton, and BG Amsden, “Additive manufacturing of photo-cross-linked structures via melt electrospinning writing” Biomacromolecules, 17(1) (2016) 277-284.
96 MC Vyner and BG Amsden, “Polymer chain flexibility-induced differences in fetuin A adsorption and its implications on cell attachment and proliferation” Acta Biomaterialia, 31 (2016) 89-98.
95 J Yang, F Chen and BG Amsden, “Cell sheets prepared via gel-sol transition of calcium RGD-alginate” Acta Biomaterialia, 30 (2016) 277-284.
94 F Chen and BG Amsden, “Homo- and co-polymerization kinetics of trimethylene carbonate bearing a methoxyethoxy side group.” J Polym Sci A Polym Chem, 54 (2016) 544-552.
93 T.Y. Han, S. Toutounji, BG Amsden, LE Flynn*, “Adipose-derived stromal cells mediate in vivo adipogenesis, angiogenesis and inflammation in decellularized adipose tissue bioscaffolds,” Biomaterials 10 125-137, 2015.
92 C. Brown, J Yan, T. Han, D. Marecak, BG Amsden, LE Flynn*, “Effect of decellularized adipose tissue particle size on adipose-derived stem cell proliferation and adipogenic differentiation in composite methacrylated chondroitin sulphate hydrogels,” Biomedical Materials 10 045010, 2015.
91 BG Amsden, “Novel biodegradable polymers for local growth factor delivery,”European J Pharm Biopharm, 97 (2015) 318-328
90 JWS Hayami, SD Waldman, BG Amsden*, “Photo-cross-linked methacrylated polysaccharide solution blends with high chondrocyte viability, minimal swelling, and moduli similar to load bearing soft tissues.” European Polymer Journal, 72 (2015) 687-697.
89 NA Hadjiev and BG Amsden*, “An assessment of the predictive ability of the obstruction-scaling model of solute diffusion coefficients in hydrogels,” J Controlled Release 199 (2015) 10-16.
88 MC Vyner, A Li, BG Amsden*, “The effect of poly(trimethylene carbonate) molecular weight on macrophage behavior and enzyme adsorption and conformation,” Biomaterials, 35(33) (2014) 9041-9048.
87 F Chen, JWS Hayami, and B.G. Amsden*, “Electrospun fibrous polymer scaffolds with stabilized crimp-like structure,” Biomacromolecules,  15(5) (2014) 1593-1601.
86 J Yang, J Yan, Z Zhou, BG Amsden*, “Dithiol-PEG-PDLLA micelles: preparation and evaluation as potential topical ocular delivery vehicle” Biomacromolecules, 15(4) (2014) 1346-1354.
85 V Russo, S Young, G. Andrew Hamilton, BG Amsden, LE Flynn*, “Mesenchymal stem cell delivery strategies to promote cardiac regeneration following ischemic injury” Biomaterials 35 (2014) 3956-3974.
84 H.K. Cheung, T. Han, D.M. Marecak, J.F. Watkins, B.G. Amsden, and L.E. Flynn*, “Composite hydrogel scaffolds incorporating decellularized adipose tissue for soft tissue engineering with adipose-derived stem cells,” Biomaterials 35 (2014) 1914-1923.
83 I.O. Babasola, M. Rooney, BG Amsden*, “Co-release of bioactive VEGF and HGF from liquid injectable poly(5-ethylene ketal É√-caprolactone-co-D,L-lactide),” Molecular Pharmaceutics 10 (2013) 4552-4559.
82 JWS Hayami, SD Waldman, BG Amsden*, “Injectable, high modulus and fatigue resistant, composite scaffold for load-bearing soft tissue regeneration,” Biomacromolecules 14 (2013) 4236-4247.
81 MC Vyner, L Liu, HD Sheardown, and BG Amsden*, “The effect of elastomer crosslink density on protein adsorption,” Biomaterials 34(37) (2013) 9287-9294.
80 I.O. Babasola, BG Amsden*, “Osmotically driven protein release from liquid injectable polymers based on 5-ethylene ketal ε-caprolactone: potential and mechanism,” Eur J Pharm Biopharm 85 (2013) 765-772.
79 C. Yu, S. Young, V. Russo, B.G. Amsden, and L.E. Flynn*, “Techniques for the isolation of high quality RNA from cells encapsulated in chitosan hydrogels,” Tissue Eng C, 19(11) (2013) 829-838.
78 L.A. Cornacchionne, B. Qi, J.Bianco, Z. Zhou,  B.G. Amsden*, “Photo-cross-linked poly(ethylene carbonate) elastomers: synthesis, in vivo degradation, and determination of in vivo degradation mechanism,” Biomacromolecules 13(10) (2012) 3099-3107.
77 D.C. Surrao, S.D. Waldman, and B.G. Amsden*, “Biomimetic poly(lactide)-based fibrous scaffolds for ligament tissue engineering,” Acta Biomaterialia 8(11) (2012) 3997-4006.
76 A. Sukarto, C. Yu, LE Flynn, B.G. Amsden*, “Co-delivery of adipose-derived stem cells and growth factor-loaded microspheres in RGD-grafted N-methacrylate glycol chitosan gels for focal chondral repair,” Biomacromolecules 13 (2012) 2490-2502.
75 O.I. Babasola, J. Bianco, and BG Amsden*, “In vivo degradation and tissue response to poly(5-ethylene ketal e-caprolactone-co-D,L-lactide)” Biomacromolecules 13 (2012) 2211-2217.
74 D.C. Surrao, J.Y.C. Fan, S.D. Waldman, and B.G. Amsden*, “A crimp-like microarchitecture improves tissue production in fibrous ligament scaffolds in response to mechanical stimuli,”  Acta Biomaterialia, 8 (10) (2012) 3704-3713.
73 A. Sukarto, BG. Amsden*, “Low melting point amphiphilic microspheres for delivery of bone morphogenetic protein-6 and transforming growth factor β-3 in a hydrogel matrix,” J Control Release 158 (2012) 23-62.
72 R. Chapanian, MY Tse, SC Pang, and BG Amsden*, “Osmotic release of bioactive VEGF from biodegradable elastomer monoliths is the same in vivo as in vitro,” J Pharm Sci 101 (2012) 588-597.
71 O.I. Babasola, BG Amsden*, “Surface eroding, liquid injectable polymers based on 5-ethylene ketal ε-caprolactone.” Biomacromolecules 12(10) (2011) 3423-3431.
70 JWS Hayami, SD Waldman, BG Amsden*, “A photocurable hydrogel-elastomer composite scaffold with bi-continuous morphology for cell encapsulation,” Macromolecular Bioscience 12 (2011) 1672-83.
69 B.G. Amsden, “Delivery approaches for angiogenic growth factors in the treatment of ischemic conditions,” Expert Opinion on Drug Delivery, 8(7) (2011) 873-890.
68 DC Surrao, AA. Khan, AJ. McGregor, JCY Fan, B.G. Amsden, SD Waldman*, “Can Microcarrier Expanded Chondrocytes Synthesize Functional Tissue In Vitro?,” Tissue Engineering A, 17 (2011) 1959-67.
67 AJ McGregor, BG Amsden, SD Waldman*, “Chondrocyte repopulation of the zone of death induced by osteochondral harvest,” Osteoarthritis and Cartilage, 19(2) (2011) 242-248.
66 DC Surrao, JWS. Hayami, SD Waldman, BG Amsden*, “Self Crimping Electrospun Polymer Fibres,” Biomacromolecules,11 (2010) 3624-3629.
65 BG Amsden*, L. Timbart, D. Marecak, R Chapanian, MY Tse, and SC Pang, ”VEGF –induced angiogenesis following localized delivery from injectable low viscosity poly(trimethylene carbonate),” J Controlled Release, 145 (2010) 109-115.
64 A. Hsieh, T. Zahir, Y. Lapitsky, B. Amsden, W. Wan, M.S. Shoichet*, Hydrogel/Electrospun Fiber Composites Influence Neural Stem/Progenitor Cell Fate, Soft Matter, 6(10) (2010) 2227-2237.
63 B. Amsden, “Liquid, injectable, hydrophobic and biodegradable polymers as drug delivery vehicles,” Invited Feature Article, Macromol. Biosci., 10(8) (2010), 825-835.
62 L. Timbart, MY Tse, SC Pang, and BG Amsden*, “Tissue response to, and degradation rate of, photocrosslinked trimethylene carbonate-based elastomers following intramuscular implantation,”  Materials Special Issue; Advances In Biomaterials 2010, 3(2), 1156-1171.
61 B. Amsden* and B. Qi, , “Anti-atherosclerotic peptide delivery from a photocrosslinkable biodegradable network,” Int. J. Pharmaceutics 388 (2010) 32-39.
60 R. Chapanian and B.G. Amsden*, “Combined and sequential delivery of bioactive VEGF165 and HGF from poly(trimethylene carbonate) based photo-cross-linked elastomers,” J. Control Release, 143 (2010) 53-63.
59 R. Chapanian, B.G. Amsden*, “Osmotically driven protein release from photo-cross-linked elastomers of poly(trimethylene carbonate) and poly(trimethylene carbonate-co-D,L-lactide).” Eur J Pharm Biopharm 74 (2010) 172–183.
58 J. Hayami, D. Surrao, S.D. Waldman, and B.G. Amsden*, “Design and characterization of a biodegradable composite scaffold for ligament tissue engineering,” J Biomed Mater Res A 92A (2010) 1407-1420.
57 R. Chapanian, M.Y. Tse, S.C. Pang, and B. Amsden*, “Long term in vivo degradation and tissue response to photo-cross-linked elastomers prepared from star-shaped prepolymers of poly(ε-caprolactone-co-D,L-lactide),” J Biomed Mater Res A 92A (2010) 830-842.
56 B. Ilagan, B.G. Amsden*, “Macroporous photocrosslinked elastomer scaffolds containing microporosity: preparation and in vitro degradation properties,” J Biomed Mater Res A 93A (2010) 211-218.
55 B.G. Ilagan, B.G. Amsden*, “Surface modifications of photocrosslinked biodegradable elastomers and their influence on smooth muscle cell adhesion and proliferation,” Acta Biomaterialia, 5(7) (2009) 2429-2440.
54 L. Timbart, M.Y. Tse, S.C. Pang, O. Babasola, B.G. Amsden*, “Low viscosity poly(trimethylene carbonate) for localized drug delivery: rheological properties and in vivo degradation,” Macromol Biosci, 9 (2009) 786-794.
53 R. Chapanian, M.Y. Tse, S.C. Pang, and B. Amsden*, ”Role of oxidation and enzymatic action in the in vivo degradation of trimethylene carbonate based photocrosslinkable elastomers,” Biomaterials 30(3) (2009) 295-306.
52 L. Timbart and B.G. Amsden*, “Functionalizable biodegradable photocrosslinkable elastomers based on 2-oxepane-1,5-dione,” J Polym Sci A Polym Chem. 46(24) (2008) 8191-8199.
51 B.G. Amsden* and A. Lau, “Siloxane based copolymers for use in two-phase partitioning bioreactors,” Can J Chem Eng, 86 (2008) 1-5.
50 B. Amsden*, G.P. Misra, M. Marshall, ND Turner, “Synthesis and characterization of biodegradable networks providing saturated-solution prolonged delivery,” J Pharm Sci, 97 (2008) 849-862.
49 B. Amsden*, “Biodegradable elastomers in drug delivery,” Expert Opinion on Drug Delivery 5 (2008) 175-187.
48 V. Wang, G Misra, and B. Amsden*, “Immobilization of a bone and cartilage stimulating peptide to a synthetic bone graft,” J Mater Sci Mater Med, 19 (2008) 2145-2155.
47 B. Amsden*, A. Sukarto, D.K. Knight, and S.N. Shapka, “Methacrylated glycol chitosan as a photopolymerizable biomaterial,” Biomacromolecules 8 (12) (2007) 3758–3766.
46 B. Amsden*, “Curable, biodegradable elastomers: emerging biomaterials for drug delivery and tissue engineering,” Soft Matter, 3(11) (2007) 1335-1348.
45 D.K. Knight, S. Shapka, and B. Amsden*, “Structure, depolymerization, and cytocompatibility evaluation of glycol chitosan,” J Biomed Mater Res A, 83A (2007) 787-798.
44 B. Amsden*, “Review of osmotic pressure driven release of proteins from monolithic devices,” J Pharm Pharmaceut Sci., 10 (2) (2007) 100-114.
43 F. Gu, RJ Neufeld, B. Amsden*, “Sustained release of bioactive therapeutic proteins from a cylindrical biodegradable elastomeric device,” J Control Release, 117 (2007) 80-89.
42 S. Sharifpoor and B. Amsden*, “Release of a water-soluble agent from low viscosity biodegradable, injectable oligomers is driven by osmotic pressure,” Eur J Pharm Biopharm, 65 (2007) 336–345.
41 F. Gu, R. Neufeld, and B. Amsden*, “Stabilization of bioactive VEGF and potentially other therapeutic proteins during a photo-initiated free radical cross-linking reaction forming biodegradable elastomers,” Eur J Pharm Biopharm, 66 (2007) 21–27.
40 F. Gu, RJ Neufeld, and BG Amsden*, “Osmotic driven release kinetics of bioactive therapeutic proteins from a biodegradable elastomer are linear, constant, similar and adjustable,” Pharm Res 23(4) (2006) 782-789.
39 Y. Zhang and B. Amsden*, “Diffusion of vitamin B12 and proteins in semidilute alginate solutions under physiological conditions,” Macromolecules 2006, 39, 1073-1078.
38 B. Amsden*, M. Y. Tse, N.D. Turner, D.K. Knight, and S.C. Pang, “In vivo degradation behavior of photo-cross-linked star-poly(ε-caprolactone-co-D,L-lactide) elastomers,” Biomacromolecules 7 (2006) 365-372.
37 A. Mikhail, S. Sharifpoor, and B. Amsden* “Initiator structure influence on thermal and rheological properties of oligo(ε-caprolactone),” J. Biomater. Sci. Polym Edn 17 (2006) 291-301.
36 A. Tomkins, M. Kontopoulou, and B. Amsden*, “Preparation and characterization of blends of star-poly(ε-caprolactone-co-D,L-lactide) and oligo(ε-caprolactone),” J Biomater Sci Polym Edn, 16 (2005)1009-1021.
35 F. Gu, H.M. Younes, A.O.S. El-Kadi, R. Neufeld, B. Amsden*, “Sustained interferon-γ delivery from a photocrosslinked biodegradable elastomer,” J. Control Release., 102 (2005) 607-617.
34 B.G. Amsden*, G. Misra, F. Gu, and HM Younes “Synthesis and characterization of a photo-cross-linked biodegradable elastomer,” Biomacromolecules, 5(6) (2004) 2479-2486.
33 B.G. Amsden*, B.G. Stubbe, F. Horkay, S.C. De Smedt, and J. Demeester, “Modeling the swelling pressure of degrading Dex-HEMA hydrogels,” J. Polym. Sci. B. Polym. Phys. 42 (2004) 3397-3404.
32 B. Amsden*, S. Wang, and U. Wyss, “Synthesis and characterization of thermoset biodegradable elastomers based on star-poly(ε-caprolactone-co-D,L-lactide),” Biomacromolecules, 5(4) (2004) 1399-1404.
31 F. Gu, B. Amsden, R.J. Neufeld, “Sustained delivery of vascular endothelial growth factor using alginate beads,” J. Control Release, 96 (2004) 463-472.
30 A. Hatefi, D. Knight, and B. Amsden*, “A biodegradable injectable thermoplastic for localized camptothecin delivery,” J. Pharm. Sci., 93 (2004) 1195-1204.
29 H.M. Younes, E. Bravo-Grimaldo, and B. Amsden*, “Synthesis, characterization and in vitro degradation of a biodegradable elastomer,” Biomaterials, 25 (2004) 5261-5269.
28 B. Amsden*, A. Hatefi, D. Knight, E. Bravo-Grimaldo, “Development of injectable biodegradable thermoplastic oligomers,” Biomacromolecules, 5 (2004) 637-642.
27 B. Amsden*, “A model for osmotic pressure driven release from cylindrical rubbery polymer matrices,” J. Control. Release. 93 (2003) 249-258.
26 B.G. Amsden, J. Bochanysz, and A.J. Daugulis*, “Degradation of xenobiotics in a partitioning bioreactor in which the partitioning phase is a polymer,” Biotechnol. Bioeng., 84 (2003) 399-405.
25 A.J. Daugulis*, B.G. Amsden, J. Bochanysz, and A. Kayssi,  “Delivery of benzene to Alcaligenes xylosoxidans by solid polymers in a two-phase partitioning bioreactor”, Biotech. Letters, 25 (2003) 1203-1207.
24 B.G. Stubbe, F. Horkay, B. Amsden, W.E. Hennink, S.C. De Smedt, and J. Demeester*, “Tailoring the swelling pressure of degrading dextran hydroxyethyl methacrylate hydrogels,”  Biomacromolecules, 4 (2003) 691-695.
23 A. Hatefi and B. Amsden*, “Camptothecin delivery systems,” Pharm. Res., 19(10) (2002) 1389-1399.
22 A. Hatefi and B. Amsden*, “Biodegradable injectable in-situ forming drug delivery systems,” J. Control Release,  80 (2002) 9-28.
21 B. Amsden*, “Modeling solute probe diffusion in polymer solutions,” Polymer  43(5) (2002) 1623-1630.
20 H.M. Younes, and B. Amsden*, “Interferon-γ therapy: Evaluation of routes of administration and delivery systems,” J. Pharm. Sci. 91(1) (2002) 2-17.
19 B. Amsden*, K. Grotheer, and D. Angl,“ Influence of polymer ionization degree on solute diffusion in polyelectrolyte gels,” Macromolecules, 35 (2002) 3179-3183.
18 B. Amsden*, “ Diffusion in polyelectrolyte hydrogels:  Application of an obstruction-scaling model to solute diffusion in calcium alginate,”  Macromolecules  34 (2001) 1430-1435.
17 B. Amsden* and N. Turner, “Diffusion characteristics of calcium alginate gels,” Biotech. Bioeng. 65 (1999) 605-610.
16 B. Amsden*,  “The production of uniformly sized polymer microspheres,” Pharm. Res. 16 (1999) 1140-1143.
15 B.G. Amsden*, “An obstruction-scaling model for diffusion in homogeneous hydrogels,” Macromolecules 32 (1999) 874-879.
14 B.G. Amsden*, “Diffusion within hydrogels. Mechanisms and models,” Macromolecules, 31(23) (1998) 8382-8395.
13 B.G. Amsden*,  “Solute diffusion in hydrogels.  An examination of the retardation effect,” Polymer Gels and Networks,  6 (1) (1998) 13-43.
12 B.G. Amsden* and M.F.A. Goosen.  “An examination of factors affecting the size, distribution, and release characteristics of polymer microbeads made using electrostatics,” J. Control. Release.  43 (1997) 183-196.
11 B.G. Amsden*,  “Osmotically activated protein release from electrostatically generated polymer microbeads.” AIChE Journal, 42 (1996) 3253-3266.
10 A.O. Okhamafe, B. Amsden, W. Chu, and M. Goosen*,  “Modulation of protein release from chitosan-alginate microcapsules using a pH-sensitive polymer”,  J. Microencapsulation  13 (1996) 497-508.
9 B. G. Amsden and M.F.A. Goosen*.  “Transdermal delivery of peptide and protein drugs: An overview,”  AIChE Journal, 41 (1995) 1833-2012.
8 B. Amsden and Y. Cheng*.  “Generic peptide delivery systems based on osmotically rupturable monoliths.”  J. Control Release,  33  (1995)  99-105.
7 B.G. Amsden, Y. Cheng, and M. Goosen*.  “A mechanistic study of the release of osmotically active agents from elastomeric monoliths.”  J. Control Release, 30 (1994) 21-32.
6 B.G. Amsden and Y. Cheng*.   “Enhanced fraction releasable above percolation threshold from monoliths containing osmotic excipients.” J. Control Release, 31 (1994) 45-56.
5 A.E. Polk, B. Amsden, F. DeYao, T. Peng, and M. Goosen*.  “Chitosan-alginate microcapsules for oral protein drug delivery.” J. Pharmaceutical Sciences, 84 (1994) 178-185.
4 A.E. Polk, B. Amsden, D.J. Scarrat, A. Gonzal, A.O. Okhamafe, and M.F.A. Goosen*,” Oral delivery in aquaculture: Controlled release of proteins from chitosan-alginate microcapsules,” Aquacultural Engineering 13 (1994) 311-323.
3 D. Poncelet, B. Bugarski, B. Amsden, J. Zhu, R. Neufeld, and M.F.A. Goosen*.  “A parallel plate electrostatic droplet generator: parameters affecting microbead size.” Applied Microbiology and Biotechnology, 41 (1994).
2 B. Bugarski, B. Amsden, R.J. Neufeld, D. Poncelet, and M.F.A. Goosen*.  “Effect of electrode geometry and charge on the production of polymer microbeads by electrostatics.”  Canadian Journal of Chemical Engineering, 72 (1994) 517-521.
1 X. Zhang, U.P. Wyss, D. Pichora, B. Amsden, and  M. Goosen*. “Controlled release of albumin from biodegradable poly(DL-lactide) cylinders.” J. Control Release, 25 (1993) 61-69.